Protein Modification Reagents
Medchemexpress LLC 2,5-dioxopyrrolidin-1-yl m-PEG24 carboxylate | 2395839-96-8 | MFCD11041155 | 99.7% | 1214.39 g·mol⁻¹ | C54H103NO28 | 5 MG
m-PEG24-NHS ester is a methoxy-terminated polyethylene glycol (PEG) linker functionalized with an N-hydroxysuccinimide (NHS) ester. The NHS group reacts with primary amines to form stable amide bonds, enabling bioconjugation and linker installation in medicinal chemistry workflows such as PROTAC assembly. The reagent is provided with high purity for research applications.
- Methoxy-terminated PEG24 linker with NHS ester reactivity.
- Reacts with primary amines to form stable amide bonds.
- Compatible with PROTAC synthesis and general bioconjugation.
- High purity suitable for research use.
- Molecular weight approximately 1214.39 g·mol⁻¹.
Medchemexpress LLC Mal-amido-PEG6-acid | 1334177-79-5 | 99.3% | 250 MG
Mal-amido-PEG6-acid is a PEG-based PROTAC linker utilized in the synthesis of PROTACs. PROTACs consist of two distinct ligands connected by a linker, where one ligand targets an E3 ubiquitin ligase and the other targets the protein of interest. These PROTACs leverage the intracellular ubiquitin-proteasome system to selectively degrade target proteins.
- Used in the synthesis of PROTACs
- Contains two distinct ligands connected by a linker
- One ligand targets an E3 ubiquitin ligase
- Other ligand targets the protein of interest
- Leverages the intracellular ubiquitin-proteasome system
- Selectively degrades target proteins
ABclonal Technology MAN1C1 Rabbit pAb
Predicted to enable mannosyl-oligosaccharide 1,2-alpha-mannosidase activity. Predicted to be involved in N-glycan processing. Located in extracellular exosome.
Medchemexpress LLC Dspe-PEG-SH | 1462982-18-8 | 90.0% | C44H86NO10PS | 1 G
DSPE-PEG-SH (MW 1000) is a thiol-functionalized pegylated phospholipid used to introduce reactive thiol groups onto lipid membranes and biomolecules. Supplied as an average MW ~1000 PEG-lipid, it is used for liposome and lipid nanoparticle preparation, surface modification, and thiol-maleimide conjugation to attach ligands or drugs.
Sigma Aldrich Fine Chemicals Biosciences Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 500ML
Guanidine hydrochloride solution, 6M Reagent designed and manufactured under cGMP controls suitable for use in an IVD application | 500ML
